Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

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Initial therapy of metastatic breast cancer with paclitaxel plus bevacizumab prolongs progression-free survival, but not overall survival, as compared with paclitaxel alone. Original article from the new england journal of medicine paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer.   infection was more common in patients receiving paclitaxel plus bevacizumab (9. Conclusions initial therapy of metastatic breast cancer with paclitaxel plus bevacizumab prolongs progression-free survival, but not overall survival, as compared with paclitaxel alone.). Infection was more common in patients receiving paclitaxel plus bevacizumab (9. Conclusions initial therapy of metastatic breast cancer with paclitaxel plus bevacizumab prolongs progression-free survival, but not overall survival, as compared with paclitaxel alone.). Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for her2-negative metastatic breast cancer (turandot) primary endpoint results of a randomised, open-label, non-inferiority, phase 3 trial. However, progression-free survival is an unreliable measure of benefit in metastatic cancer, and patients given bevacizumab do not live longer than patients given paclitaxel alone.

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